VSL Probiotics: ALegacy of Science in Every Strain.
VSL#3Benefits:
A Clinically Studied Medical Food
VSL#3 is a medical-grade formulation supported by clinical research.
Ultra-High Potency, Guaranteed
Contains 112.5 billion live bacteria (CFU) per capsule — an ultra-high-potency formula designed to keep its labeled potency through expiration when stored under recommended conditions.
Multi-Strain
8 complementary strains from 3 different genera.

Clean Ingredients. Trusted Standards.
Clean Ingredients. Trusted Standards.
Dairy-Free
Gluten-Free
Soy-Free
Nut-Free
No GMOs
Vegan
The VSL Probiotics Difference
Medical Foods & Supplements
From medical foods formulated for the dietary management of Gl conditions to supplements for daily wellness, VSL Probiotics is made to the highest standards of quality and consistency.
Proven Potency
Up to 900 billion live bacteria per serving — verified to maintain labeled CFU counts through expiration when stored as recommended.
Evidence-Based Formulations
Formulated with probiotic strains and combinations supported by published research and guided by microbiome science.
Trusted by Professionals
Rooted in the heritage of VSL#3—a probiotic trusted by healthcare professionals—VSL Probiotics carries that same dedication to quality and research into every new formulation.
VSL#3 Capsules are an ultra-high-potency probiotic medical food formulated to support the dietary management of IBS and ulcerative colitis. Each capsules provides 112.5 billion live bacteria from 8 clinically studied probiotic strains working together.
FAQS
What is VSL#3R?
What is VSL#3R?
VSL#3R is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).
How should I store VSL#3R?
How should I store VSL#3R?
VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.
What is a Medical Food?
What is a Medical Food?
Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.
How does VSL#3 compare to a Low FODMAP diet for IBS management?
How does VSL#3 compare to a Low FODMAP diet for IBS management?
In a 2021 clinical study, VSL#3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 — a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.