
More Than a Probiotic. A Powerful Medical Food.
Pioneers in Probiotics. Leaders in Gut Health.
VSL#3 is an ultra-high-potency probiotic medical food - and the #1 gastroenterologist-recommended multi-strain probiotics brand. Developed for people with serious gastrointestinal conditions, it's trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.
Built on Science. Proven in Practice.
Driven by research - not marketing trends —VSL#3 is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.
Ultra-High-Potency. Guaranteed.
VSL#3 products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3 guarantees potency through expiration when stored asdirected.
Clinically Researched Formulas. Real-World Results.
Each VSL#3 product combines 8 well-characterized probiotic strains from 3 genera to help maintain a balanced intestinal microbiota and support digestive health. The VSL#3 family is specially designed for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and pouchitis.
Why Doctors Trust VSL#3
VSL#3 Is Scientifically Formulated For The Dietary Management of IBS
Doctor Recommended
In a 2002 survey of gastroenterologists, 93% reported that IBS patients were satisfied with VSL#3.
The most frequently observed benefits:
- Less bloating
- Reduced pain
- Better stool consistency and frequency
- Overall symptom improvement
Clinically Studied and FODMAP Friendly Certified for the Dietary Management of IBS
In a 2021 clinical study, VSL#3R showed outcomes comparable to those achieved with a low FODMAP diet2 - a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1. Data on file 2. Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.
It's What's on the Inside
Our unique 8-strain formulation is designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.
Clean Ingredients. Trusted Standards.
Clean Ingredients. Trusted Standards.
Dairy-Free
Gluten-Free
Soy-Free
Nut-Free
No GMOs
Vegan
VSL#3 Capsules: Clean Ingredients. Verified Quality.
Free From Common Irritants:
- Dairy-Free
- Gluten-Free
- Soy-Free
- Nut-Free
- No GMOs
- Vegan
Certified for Peace of Mind:
- FODMAP Friendly Certified
- Halal Certified
- Kosher Certified
FAQS
What is VSL#3R?
What is VSL#3R?
VSL#3R is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).
How should I store VSL#3R?
How should I store VSL#3R?
VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.
What is a Medical Food?
What is a Medical Food?
Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.
How does VSL#3 compare to a Low FODMAP diet for IBS management?
How does VSL#3 compare to a Low FODMAP diet for IBS management?
In a 2021 clinical study, VSL#3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 — a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.